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Organic compounds that contain a carbon atom bonded to a halogen atom, and an oxygen atom via a double bond; commonly derived from an oxoacid by replacing a hydroxyl group with a halogen atom.
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A derivative of guanosine; a precursor in the synthesis of hydrophobic dinucleotide cap analogs used to purify capped mRNA; a precursor in the synthesis of photocaged 3’-S-RNAs used in the study of ribozyme-catalyzed reactions
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Umeclidinium bromide is a novel mAChR antagonist with an affinity (Ki) for cloned human M1-M5 mAChRs ranging from 0.05 to 0.16 nM. It inhibits the human ether-a-go-go-related gene channel tail current in a concentration-dependent manner.
Novel mAChR antagonist
Inhibits human ether-a-go-go-related gene channel tail current
Shows slow functional reversibility at cloned human M3 mAChRs
Shows slow functional reversibility at endogenous mAChR in isolated human bronchus
For research use only
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A membrane-impermeant lidocaine derivative that when combined with capsaicin selectively blocks sodium channels on nociceptive neurons via the TRPV1 channel; decreases the pain response without imparting numbness or paralysis associated with other local anesthetics
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1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium) is a palmitoyl lysophosphatidylglycerol (lyso-PG) lipid supplied as the sodium salt for biochemical and lipid research. It is a white to off-white solid with molecular formula C22H44NaO9P, molecular weight 506.54 Da, and nominal purity 99.0%. Recommended storage is -20°C (sealed, away from moisture); in solvent: -80°C up to 6 months or -20°C up to 1 month.
High purity (99.0%) suitable for analytical and preparative work
Lyso-PG lipid useful for membrane and signaling studies
White to off-white solid; easy to weigh and handle
Stable when stored sealed at -20°C; extended storage in solvent at -80°C
Available in small research quantities for laboratory experiments
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A membrane-impermeant lidocaine derivative that when combined with capsaicin selectively blocks sodium channels on nociceptive neurons via the TRPV1 channel; decreases the pain response without imparting numbness or paralysis associated with other local anesthetics
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Butyryl-L-carnitine-d3 chloride is the deuterium-labeled form of butyryl-L-carnitine (chloride) intended for use as a tracer or internal standard in quantitative analytical methods. It is supplied in small milligram quantities with high isotopic and chemical purity for laboratory research and method development.
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Ipratropium bromide (CAS 22254-24-6) is a synthetic quaternary ammonium compound structurally derived from atropine It functions as a muscarinic acetylcholine receptor (mAChR) antagonist primarily inhibiting M3 receptor-mediated bronchoconstriction in airway smooth muscle By blocking parasympathetic-mediated bronchial smooth muscle contraction it induces bronchodilation Ipratropium bromide is widely utilized in research to investigate cholinergic signaling pathways airway physiology and the pharmacological modulation of bronchomotor tone Its properties make it valuable for studies focused on obstructive pulmonary conditions and respiratory drug development
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